Millenial: Weren't the Tzimisce wiped out by modern times in Vampire: The Masquerade - Redemption? Or am I think of the Capadocians?
Old clan Tzimisce were hunted to almost extinction, by the rebellion. But they still survive, typically in self-imposed isolation and are usually powerful elders, unaffiliated with any factions, mostly neutral. "New" clan Tzimisce are the fleshcrafters found in the Sabbat, with relative abundance at that, too. Both have their merits, though and the occasional RP uniqueness, special touch.
Cappadocians were wiped out and completely overtaken, by the Giovanni. The corrupt necromancers, rich Italian mafia type peeps. Likewise, the Tremere creepy mages came to be, after almost wiping out the Salubri bloodline (healers; their clan leader who had been diablerized by Tremere himself, was consider to be something like a saint for the damned).